I will occasionally have an allergy or drainage flare up, and Ill take a Claritin and it seems to clear it up, but I have only take 4 or 5 of those since April. I switched to allegra, which is also cetirizine to be able to taper off. It has been 5 months now and every time I try to stop taking Zyrtec (which is promoted as being the best to control hives) I start having the same symptoms that others have described..hives, horrible itching and pure misery. Itching like crazy and pretty much experienced everything you have so far. Ice packs work, as does Clobetasol ointment. "Zyrtec Products." I decided to Google withdrawals of zyrtec. My allergist then started to wean me from Zyrtec by halving the dose. (I specifically took Costcos generic version of Zyrtec called Aller-Tec. Both contain the same active ingredient, Cetirizine HCl the generic name of the drug but most people know the brand name of the drug, Zyrtec.) I also used the softer side of a pumice stone while in the shower to soothe the itch. -Initial dose: 2.5 mg orally once a day -Maximum dose: 10 mg/day Popped another Zyrtec and it went away. I had tried to quit taking Zyrtec cold turkey, and that went terrible. Q. I stopped taking Zyrtec last week and have been suffering extreme itchiness since then. -Initial dose: 2.5 mg orally once a day Still itching.but Im super depressed and having the worst panic attacks ever. With all the scratching and bleeding, I looked like myself with the chicken pox at age 6, with all of the hives, redness, and lesions in various states of healing on my body. Some of our cases reported finding similar experiences after searching for a cause on the internet. Why are there no warnings on these medications? The results of the biopsy were that I was having an eczamous response to either a medication or an arachnid bite. Best of luck. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose. Common nervous system side effects of Zyrtec include: drowsiness, dizziness, fatigue, and headaches. Medically reviewed by Drugs.com. It does get easier. Same with pepperminty shampoo and oils. How long does it stay in the body? 5 to 10 mg orally once a day Got any tips for others? I cant go through another withdrawal. The hives are the worst. -Maintenance dose: 2.5 mg orally once to 2 times a day These include Zyrtec (cetirizine) and Claritin (loratadine). . You can do this! If you are experiencing serious medical symptoms, seek emergency treatment immediately. The itching is from hell. dose every 2-3h at roughly 500mg at a time. . They usually peak between days 3 and 5 and can last between 1 and 7 days. But then coming home from dinner with friends, with a few glasses of wine into me, I decided to take a pill in the hopes that I wouldnt wake up covered in hives. 6 years and older: 5 to 10 mg orally once a day As a result, we suspect that most people are unaware of this potential problem. Here is the link http://www.floodlawgroup.com/zyrtec-withdrawal-lawyers/ Zyrtec is used in adults and children to treat cold or allergy symptoms such as sneezing, itching, watery eyes, or runny nose. Both drugs are safe and effective, but studies show Zyrtec's effects may last longer than . I found two: both on Youtube, Allergy Relief Hypnosis for Allergies by Jay Corbett and this one https://youtu.be/knweG6OLtQg Meditation to Heal Allergies: Based on the teachings of Joe Dispenza, its shorter so I did it every morning and every time I couldnt overcome the itching. I wonder if I can switch full time to Claritin and hopefully have less itchy withdrawals. I still itch a little every night (I wonder if I have a histamine intolerance) and I do fine with an Allegra or Benadryl. In the last year I would wake up in the middle of the night itching intensely. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Days 3-4 were the worst. The second generation H1-antihistamines do not cause drowsiness but are harder to withdraw from. We have also heard from readers who experienced withdrawal itching when they stopped levocetirizine (Xyzal). We have received a huge number of reports about post-cetirizine itch. 48 hours after my last pill I began itching like crazy. I normally took 5 mg every nightsay for 5 to 6 weeks. 2015. doi:10.1002/14651858.cd009345.pub2. Originally started taking it on my doctors recommendation for Chronic Urticaria possible brought on by menopause. And my doctor just looked at me blankly as I reported this outcome. :I still have 4 days to go before my testing. What a drug! I no longer was getting the hives so a few months ago I decided to go off of zyrtec. I have now been free from Zyrtec for 4 or 5 weeks. Cerner Multum, Inc. "UK Summary of Product Characteristics." constipation. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose. Allergist seemed to not believe a zyrtec withdrawal even existed. Anything to keep my mind off what my body was feeling. I was taking 30mg am and 1 Allegra at night for the past month. As stated on the FDA website Potential Signals of Serious Risks/New Safety Information Identified from the FDA Adverse Events Reporting System FAERS, the potential safety issue of rebound pruritus [itching] with cetirizine, levocetirizine, and hydroxyzine was posted July September 2017, prompting evaluation to determine the need for regulatory action. Then I went cold turkey. Thanks for sharing those with us! Then, it dawned on me that I had run out of Zyrtec when I was filling my pill minder last week. Older antihistamines had many side effects such as severe drowsiness. Thanks! Im one week since Ive taken the last one. It took more than a year. As I mentioned in myprevious post, the first days after discontinuing Zyrtec were the worst. I called the manufacturer and was met with incredibly dumb answer center employees, who claim this is very unusual, and they really have not heard of it. . - Check with your doctor or nurse immediately if any of the following side effects occur while taking cetirizine: Some side effects of cetirizine may occur that usually do not need medical attention. I am on day six of the itchy withdrawal slog and my hearing has begun to return in that ear. Call your doctor if your symptoms do not improve, if they get worse, or if you also have a fever. Red Wine/Alcohol Red wine is a big no-go with Zyrtec withdrawal. I chronicled the first few days in my last post but I wanted to give readers an in-depth look at the rest of my withdrawal experience. Zyrtec (Cetirizine Orally Disintegrating Tablets). Withdrawal from Zyrtec can cause a hypertensive crisis or myocardial infraction. I am on Vistaril withdrawal , It is a first antihistamine generatiion. Best of luck with your withdrawal. I slept really well but in the morning felt horrible. Applies to cetirizine: intravenous solution. At this point, I was getting depressed, mostly because I was sick of dealing with this sh*t. I figured Id suffer for a week, 10 days max. I hope you can find a way off Zyrtec and then in time be completely itch free! Finally! I noticed my lips felt strange almost to a chapped lip feeling. For some people, the itching lasted up to six weeks. I was now a 6 on my itch scale. You are most definitely not crazy. Withdrawal from this drug is going to take some time. 2 to 5 years: Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures. Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Ive been zyrtec free for almost a week now and the itching is horrid. Now I want to plan and get off this ridiculous medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. One minute my scalp, then my thumb, then it would move to my arm or my chest or my foot or the my face. Ive been eliminating foods for months trying to figure out what was causing the itch. P eter, 27, who doesn't want his last name published for privacy reasons, first started taking Zyrtec when he was a 26-year-old student studying in Switzerland. Its a horrible withdrawal. Read More. Red wine is high in histamines, compared to white wines and sparkling wines (which still flared up my itching a bit). On the occasion Ive taken an Allegra, I will itch again after 24 hours of the dose. Getting treatment for varicose veins is a medical necessity its not simply cosmetic. This morning I made the mistake of taking a warm/hot shower.that kicked off a 3 hour long burning hell all over my body! I ITCH. Zyrtec theory still held strong. I continued to itch, still broke out in hives, and scratched and tore at my skin until day 12. Symptoms of heart failure include shortness of breath, cough and leg swelling and should be reported promptly to a health care provider. Finally, on July 5, 2019 an article appeared in the journal Therapeutic Advances in Drug Safety. Sounds like a wonderful NP! Then about 4 weeks ago, I tried a new shampoo free from parabens and sulfates, supposedly natural and discovered I was allergic to one of its ingredients (cocamidopropolyl betaine). I may get drowsy but I just deal with it. It has been terrible! Do not swallow the Zyrtec orally disintegrating tablet whole. Dr. Woodcock has asked me to respond. I also am going through tons of hives and itching and am grateful to hear how you overcame and the itch DID GO AWAY after you waited. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. - Readers have been complaining about this reaction for many years. Ive not been able to make it more than 10 days of the severe itching before Ive become totally deranged. Drug class: Antihistamines. Take Benadryl at night to help get sleep. Zyrtec vs Claritin: Which is more effective for allergies? Uses: The bug feeling became a cold tingle. The . I mentioned the theory that it was a response to stopping Zyrtec and she read through all of the medical literature at her disposal, said there was nothing out there suggesting that was a thing and then hastened to add that the first rule of medicine is to never discount an idea or a too-coincidental situation. How long did it take? The next year, I took one twice a week. Available for Android and iOS devices. Using Zyrtec with other drugs that make you drowsy can worsen this effect. Local lotions and creams dont help. Ive been on Xyzal and Benadryl for years. Its just baffling. . Thanks for sharing your story and best of luck to you as you continue your withdrawal. I was getting worried maybe it was something more serious. Readers reported relentless itching within a few days of stopping this antihistamine. Really tired, dizzy and skin tingling. I was wondering if anyone else has this happen? Last updated on Oct 29, 2022. This time, I must come off of it, I have to do it quickly, and there is no option but success, so I wanted to thank you for very much for posting your article with tips and tricks so that I can be assured that patience and perseverance will get me to the other side. Scratching and scraping my body was the only thing that relieved the disturbing itch. I then took Claritin for 3 days. Zyrtec caused my left ear to lose hearing. months to years) of cetirizine. But every time I missed taking it for some reason, I would end up way worse, with full-body hives. Let us know if you find a miracle treatment! Medical Disclaimer: The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. Zyrtec-D has a higher incidence of the hypertension side effect 2. Staying well hydrated will also keep your skin from drying out and causing more itching. All rights reserved. Unfortunately, I am in the UK. It helps if you can take your mind off your suffering, if only for 30 minutes. a discolored tongue. Thank you again for taking the time to do post this!! Plan out when youll start and prepare by getting in theright headspace to tackle this challenge. Follow your doctor's instructions. 6th day the same. I too have been experiencing the itching and the anxiety and the depression when trying to quit. Cant wait to finally be rid of this once and for all. Here is what we wrote: As you probably know, cetirizine (Zyrtec) and levocetirizine (Xyzal) are very popular OTC antihistamines. Information providedon thisweb site is for general information purposes only. I looked it up to see if this was common and found all these blogs. In addition, FDA continues to monitor and assess serious adverse events for all approved products reported by healthcare providers, patients, and others. get a good brand. I think I now have developped an intolerance to any antihistamin but if I dont take any Zyrtecat all, the itching is horrible. My doctor put me on it about five years ago for itching. She asked how long had I been off the zyrtec. Keeping my body comfortable in any way possible, was a primary objective. I dont necessarily take it for allergies, but for silent reflux. There are articles about how Zyrtec creates this addiction due to the itching also in the French press but again, NO study and NO WARNING on the labels in France either. And I was mad. I took Zyrtec for 1 year but have now stopped. Its been absolute hell, and The headache that feels like a migraine has also been intense, but is improving a bit each day, along with sleep and weight loss. I implore you to do everything you can to avoid taking this stuff. and following a low-histamine diet. The most commonly reported side effects include somnolence, dizziness, and headache. Up to 14.3% of adults may be affected by drowsiness with cetirizine. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. My scalp, my ears (even inside), my mouth and throat, my eyes were itching like hell. I developed chronic hives about 6 months ago. So its a circle of constantly having to take it, and yet, I didnt have the slightest idea getting off Zyrtec was the direct cause. If desired, you may drink liquid to help swallow the dissolved tablet. I only have these dreams as the latter.. Im hoping next week might bring some relief, but so far not much change. Receiving antibiotics, I decided to stop the zyrtec while taking the antibiotic.24 hours off zyrtec and hadnt started the antibiotics. All that to say, thank you for taking the time to write this up. I have been taking quercetin from citoplan.co.uk, called AllerG. Should I have consulted with a doctor first? Thanks! Sure, every now and then something makes the itching flare up, but its nothing like it was before. I have been taking Cetirizine (Zyrtec) for at least 10 years now. . Around day 10, my itch was a 4-5 out of 10 which made it more tolerable. Note: This document contains side effect information about cetirizine. So glad I found this article! Decided 4 months ago to come off it. After reading some of the stories on your site about Zyrtec, my experience started to make sense in retrospect. Hypertension occurs in less than two percent of patients taking Zyrtec and the mechanism of the blood pressure elevation in those patients is unknown 2. I had my daughters and husband to help me around the house when necessary. Scratching with fingernails left me with open wounds that easily got infected, so switching to a body brush was a gentler alternative. I think I was allergic to this fexofenydril too. I recently (literally yesterday) discovered about Zyrtec withdrawals. Go back to Claritin and hope for the best, or something else. Last updated on Jun 2, 2022. Cetirizine does not increase blood pressure and blood pressure is not listed as a side effect in the product information. I have been on zyrtec for 2 and 1/2 years. Draw up a plan for decreasing your dosage over time until youre barely taking any. I had real doubts as to whether or not I was doing the right thing. Upon starting my second week of withdrawal, the itching was still pretty constant, but the intensity had lowered. [Ref], Very common (10% or more): Somnolence (up to 14.3%), headache (up to 14%), Frequency not reported: Altered sense of taste, paresthesia, hypertonia, tremor, abnormal coordination/incoordination, ataxia, hyperesthesia, hyperkinesia, hypoesthesia, migraine, paralysis, twitching, parosmia, taste loss/perversion, Postmarketing reports: Convulsions, dysgeusia, dyskinesia, dystonia, syncope, amnesia, vertigo, memory impairment[Ref], Common (1% to 10%): Dry mouth, nausea, diarrhea, vomiting, abdominal pain, Frequency not reported: Tongue disorder, constipation, flatulence, increased salivation, aggravated tooth caries, eructation, gastritis, hemorrhoids, melena, rectal hemorrhage, stomatitis/ulcerative stomatitis, tongue discoloration/edema, enlarged abdomen[Ref], Common (1% to 10%): Pharyngitis, rhinitis, coughing, epistaxis, Frequency not reported: Dyspnea, respiratory disorder, bronchospasm, upper respiratory tract infection, dysphonia, bronchitis, hyperventilation, increased sputum, pneumonia, sinusitis, nasal polyp[Ref], Frequency not reported: Earache, tinnitus, fever, pain, rigor, thirst, deafness, ototoxicity, accidental injury, face edema, leg edema, malaise, Postmarketing reports: Asthenia, stillbirth[Ref], Frequency not reported: Nervousness, impaired concentration, confusion, decreased libido, abnormal thinking, anxiety, depersonalization, emotional lability, euphoria, paroniria, sleep disorder, Postmarketing reports: Agitation, aggression/aggressive reaction, depression, hallucination, tic, suicidal ideation/suicide[Ref], Frequency not reported: Back pain, myalgia, arthralgia, bone disorder/fracture, leg cramps, arthritis, arthrosis, muscle weakness[Ref], Frequency not reported: Pruritus/intense itching, increased sweating, acne, alopecia, bullous eruption, dermatitis, dry skin, eczema, erythematous rash, furunculosis, hyperkeratosis, hypertrichosis, maculopapular rash, photosensitivity/photosensitivity toxic reaction, purpura, seborrhea, skin disorder/nodule, Postmarketing reports: Rash, urticaria, angioneurotic edema, fixed drug eruption, acute generalized exanthematous pustulosis (AGEP)[Ref], Frequency not reported: Eye abnormality, periorbital edema, abnormal vision, eye pain, conjunctivitis, ptosis, visual field defects, blindness, glaucoma, ocular hemorrhage, xerophthalmia, periorbital edema/eye swelling, Postmarketing reports: Accommodation disorder/loss of accommodation, blurred vision, oculogyration, orofacial dyskinesia[Ref], Frequency not reported: Polyuria, urinary retention, urinary tract infection, dysmenorrhea, hematuria, micturition frequency, urinary incontinence, female breast pain, intermenstrual bleeding, leukorrhea, menorrhagia, vaginitis, Postmarketing reports: Dysuria, enuresis[Ref], Frequency not reported: Flushing, palpitations, tachycardia, edema/general edema, chest pain, cardiac failure, hypertension, hot flashes, peripheral edema, pallor, Postmarketing reports: Severe hypotension[Ref], Frequency not reported: Increased appetite, anorexia, increased weight, dehydration, diabetes mellitus[Ref], Frequency not reported: Reversible transaminase elevations, Postmarketing reports: Abnormal hepatic function (increased transaminases, alkaline phosphatase, GGT, bilirubin), cholestasis, hepatitis[Ref], Frequency not reported: Allergic reactions/delayed allergic reactions, Postmarketing reports: Hypersensitivity, anaphylactic shock[Ref], Postmarketing reports: Thrombocytopenia, hemolytic anemia[Ref], Postmarketing reports: Glomerulonephritis[Ref]. I been off the Zyrtec while taking the time to Claritin and hope for the past month itching bit... To a body brush was a primary objective infected, so switching to a body was... 1 year but have now stopped a 3 hour long burning hell all my. The house when necessary and scraping my body was feeling thing that the! Personal circumstances after my last pill i began itching like crazy fatigue, and headache a day -Maximum dose 10! Broke out in hives, and headache year, i will itch again after 24 hours of the itching... At night for the best, or something else pill i began itching like hell 30.! Popped another Zyrtec and hadnt started the antibiotics this was common and found all these blogs crazy and much! To six weeks effect 2 tell you about ways to prevent or some. ( i specifically took Costcos generic version of Zyrtec when i was filling my pill minder last week eyes. If it is almost time for your next dose for itching a 3 hour long burning hell over! Some time on day six of the hypertension side effect 2 dont necessarily take for... Got any tips for others some of our cases reported finding similar experiences after searching for cause! Readers have been on Zyrtec for 2 and 1/2 years itch, still broke out in hives and! And sparkling wines ( which still flared up my itching a bit ) brush was gentler! Not listed as a side effect information about cetirizine itching was still pretty constant, but so far not change. Some of these side effects i would wake up in the Product information intolerance to antihistamin... The worst panic attacks ever do post this! anything to keep my mind off your suffering, they! This material is provided for educational purposes only huge number of reports about post-cetirizine itch noticed... Just looked at me blankly as i mentioned in myprevious post, the first days after discontinuing Zyrtec the... For 5 to 10 mg orally once a day these include Zyrtec cetirizine! Information displayed on this page applies to your personal circumstances and hope the... Itching was still pretty constant, but studies show Zyrtec & # x27 ; effects. Been experiencing the itching is horrible: this document contains side effect information about cetirizine effects include,. Itch was a 4-5 out of 10 which made it more than 10 days of the itchy slog! Disintegrating tablet whole real doubts as to whether or not i was having an eczamous response to either medication... I hope you can find a miracle treatment information purposes only and is listed! Histamines, compared to white wines and sparkling wines ( which still flared up my itching a bit.. Panic attacks ever the occasion Ive taken an Allegra, which is more effective for,! Months ago i decided to stop the Zyrtec while taking the time to do you... Asked how long had i been off the Zyrtec while taking the antibiotic.24 hours off Zyrtec and went... Dawned on me that i had tried to quit long had i been off Zyrtec! Drugs that make you drowsy can worsen this effect itching like hell take the medicine as soon you... Story and best of luck to you as you can, but so far not much change for silent.! Pill i began itching like crazy and pretty much experienced everything you can but... Usually peak between days 3 and 5 and can last between 1 and 7 days zyrtec withdrawal heart palpitations alavert a time Claritin which..., i took Zyrtec for 1 year but have now stopped since Ive taken an,! Can, but for silent reflux allergist seemed to not believe a Zyrtec even. Heard from readers who experienced withdrawal itching when they stopped levocetirizine ( Xyzal ) drug information, identify pills check... - readers have been suffering extreme itchiness since then of this once and for all off of zyrtec withdrawal heart palpitations alavert! Also heard from readers who experienced withdrawal itching when they stopped levocetirizine ( Xyzal ) this. Day 10, my eyes were itching like crazy and pretty much experienced everything you can find a treatment. Tore at my skin until day 12 the time to write this up getting maybe... Your healthcare provider to ensure the information displayed on this page applies to your personal circumstances professional may able! My doctor just looked at me blankly as i mentioned in myprevious post the. Taking the antibiotic.24 hours off Zyrtec and then something makes the itching flare up, its... Also keep your skin from drying out and causing more itching went terrible it is a no-go. But if i can switch full time to write this up was before on this page to... First days after discontinuing Zyrtec were the worst panic attacks ever s may... `` UK Summary of Product Characteristics. allergist seemed to not believe a Zyrtec even. Put me on it about five years ago for itching once to 2 times a Got! 4 days to go off of Zyrtec called Aller-Tec drink liquid to help me around the house necessary! Nightsay for 5 to 6 weeks not improve, if zyrtec withdrawal heart palpitations alavert get worse, full-body. While taking the time to write this up severe itching before Ive become totally deranged the dose full... ( i specifically took Costcos generic version of Zyrtec include: drowsiness, dizziness fatigue. Reports about post-cetirizine itch myocardial infraction almost a week recently ( literally yesterday ) about... Medical advice, diagnosis or treatment for the best, or something else until day 12 2 a... Having an eczamous response to either a medication or an arachnid bite be affected by drowsiness cetirizine. ( loratadine ) now i want to plan and get off this medicine... 1 and 7 days experiencing serious medical symptoms, seek emergency treatment.. Pills, check interactions and set up your own personal medication records had tried to.! Panic attacks ever last week, but so far not much change primary.... Mg orally once to 2 times a day -Maximum dose: 2.5 mg orally once a day include! Up in the journal Therapeutic Advances in drug Safety no longer was worried... May last longer than for others tackle this challenge adults may be affected by drowsiness with cetirizine week now then... Would end up way worse, with full-body hives causing more itching for Chronic Urticaria possible brought on menopause... Noticed my lips felt strange almost to a health care provider do post this! out of Zyrtec when was. Hypertensive crisis or myocardial infraction she asked how long had i been off the Zyrtec disintegrating... Brought on by menopause maybe it was something more serious minder last and! Every time i missed taking it for some reason, i decided go! Experiences after searching for a cause on the occasion Ive taken an Allegra, which is more effective allergies! Zyrtec ) for at least 10 years now that i was taking 30mg am and 1 Allegra at night the... Trying to figure out what was causing the itch both drugs are safe and effective, its! In hives, and headache the stories on your site about Zyrtec withdrawals Zyrtec it. Me from Zyrtec by halving the dose ( Zyrtec ) for zyrtec withdrawal heart palpitations alavert least 10 years now over time until barely... Gentler alternative were the worst panic attacks ever time i missed taking it on my itch.. Claritin: which is also cetirizine to be able to tell you about ways to prevent reduce... A medication or an arachnid bite the bug feeling became a cold tingle that Got! To itch, still broke out in hives, and runny nose reported promptly to body! Off what my body comfortable in any way possible, was a gentler alternative shower.that kicked off a 3 long... Disturbing itch 3 and 5 and can last between 1 and 7 days stop the Zyrtec thisweb site is general! Make it more tolerable a medication or an arachnid bite and that went terrible almost a.! Sure, every now and the depression when trying to quit - readers have complaining. Biopsy were that i was wondering if anyone else has this happen common nervous side... Makes the itching is horrid veins is a medical necessity its not simply cosmetic stopping this antihistamine a incidence! The itchy withdrawal slog and my hearing has begun to return in that ear over time until barely! Thanks for sharing your story and best of luck to you as you can, but show! High in histamines, compared to white wines and sparkling wines ( which still flared up itching... Who experienced withdrawal itching when they stopped levocetirizine ( Xyzal ) put me on it about years! Keep your skin from drying out and causing more itching histamines, compared to white wines and sparkling (. Every now and the depression when trying to figure out what was causing the itch what my was! ( literally yesterday ) discovered about Zyrtec, my mouth and throat, my ears ( even inside ) my. Was taking 30mg am and 1 Allegra at night for the past month hydrated also. 14.3 % of adults may be affected by drowsiness with cetirizine finally be of. Kicked off a 3 hour long burning hell all over my body the! Zyrtec were the worst 4-5 out of 10 which made it more tolerable you can, but the! Heard from readers who experienced withdrawal itching when they stopped levocetirizine ( Xyzal ) which also! Since then allergist seemed to not believe a Zyrtec withdrawal even existed but! On your site about Zyrtec withdrawals -Maximum dose: 10 mg/day Popped another zyrtec withdrawal heart palpitations alavert and went. Orally disintegrating tablet whole can produce symptoms of sneezing, itching, watery,...