Contraindicated. Use Caution/Monitor. Use Caution/Monitor. Methylphenidate may diminish antihypertensive effects. Risk of acute hypertensive episode. The generic drug name of Concerta is methylphenidate. Monitor BP. Contraindicated. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Use Caution/Monitor. Contraindicated. Other (see comment). Methylphenidate may diminish antihypertensive effects. CNS stimulant should be discontinued at least 48 hours before myelography, should not be used for the control of nausea or vomiting during or after myelography, and should not be resumed for at least 24 hours postprocedure. Methylphenidate may diminish antihypertensive effects. Applies only to oral form of both agents. Comment: Potential for additive CNS effects. dexmethylphenidate increases effects of methylphenidate by pharmacodynamic synergism. This drug is available at the lowest co-pay. Use Caution/Monitor. Monitor BP. Methylphenidate may diminish antihypertensive effects. Comment: Methylphenidate may increase serotonin release of agents with serotonergic activity, which increases the risk of serotonin syndrome or serotonin toxicity. Modify Therapy/Monitor Closely. Monitor BP. omeprazole decreases effects of methylphenidate by enhancing GI absorption. Methylphenidate may diminish antihypertensive effects. clozapine increases toxicity of methylphenidate by pharmacodynamic antagonism. Use Caution/Monitor. Avoid or Use Alternate Drug. Risk of acute hypertensive episode. Use Caution/Monitor. Risk of cardiac arrhythmia or sudden death, more likely w/thioridazine than other phenothiazines. Methylphenidate is contraindicated during treatment with an MAOI and also within a minimum of 14 days following discontinuation of an MAOI. Individual plans may vary apomorphine, methylphenidate. methylphenidate increases effects of warfarin by unspecified interaction mechanism. ropinirole, methylphenidate. Use Caution/Monitor. Use Caution/Monitor. Monitor Closely (1)hydrocodone, methylphenidate. Contraindicated. Share cases and questions with Physicians on Medscape consult. methylphenidate will decrease the level or effect of terazosin by pharmacodynamic antagonism. If you log out, you will be required to enter your username and password the next time you visit. Use Caution/Monitor. Potential for additive CNS stimulation. Monitor Closely (1)methylphenidate will decrease the level or effect of phentolamine by pharmacodynamic antagonism. Use Caution/Monitor. Avoid or Use Alternate Drug. Concerta releases about a third of its active compound in the morning and about 2/3 in the afternoon. Interaction more likely in certain predisposed pts. only. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Risk of acute hypertensive episode. Capsule with multilayer beads; 40% of dose in the immediate-release layer and 60% in the extended-release layer (2nd peak at 7-8 hrs) 12 hours. Use Caution/Monitor. only. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. Monitor Closely (1)pimavanserin increases toxicity of methylphenidate by pharmacodynamic antagonism. perphenazine, methylphenidate. Either increases effects of the other by pharmacodynamic synergism. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Use Caution/Monitor. Use Caution/Monitor. Narcolepsy is a rare sleep condition that can cause the following symptoms: excessive daytime . Use Caution/Monitor. Risk of cardiac arrhythmia or sudden death, more likely w/thioridazine than other phenothiazines. Methylphenidate is contraindicated during treatment with an MAOI and also within a minimum of 14 days following discontinuation of an MAOI. methylphenidate will decrease the level or effect of ramipril by pharmacodynamic antagonism. Monitor Closely (1)methylphenidate will decrease the level or effect of benazepril by pharmacodynamic antagonism. Applies only to oral form of both agents. This drug is available at a higher level co-pay. Methylphenidate may diminish antihypertensive effects. Use Caution/Monitor. Table 3: Dosage Conversions of Various Methylphenidate Formulations QD = once daily, BID=twice daily, TID=three times daily, QAM=every morning Adapted from product labeling Conclusion Use Caution/Monitor. Applies only to oral form of both agents. Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor. Risk of acute hypertensive episode. Monitor Closely (1)paliperidone increases toxicity of methylphenidate by pharmacodynamic antagonism. Contraindicated. Use Caution/Monitor. Applies only to extended release formulation. If concomitant use is warranted, carefully observe the patient, particularly during treatment initiation and dose adjustment. Methylphenidate may diminish antihypertensive effects. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Use Caution/Monitor. Monitor Closely (1)dexlansoprazole decreases effects of methylphenidate by enhancing GI absorption. ozanimod increases toxicity of methylphenidate by sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Monitor Closely (1)thiothixene increases toxicity of methylphenidate by pharmacodynamic antagonism. methylphenidate will decrease the level or effect of candesartan by pharmacodynamic antagonism. Risk of acute hypertensive episode. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. ephedrine and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Minor/Significance Unknown. Monitor Closely (1)methylphenidate will decrease the level or effect of terazosin by pharmacodynamic antagonism. Monitor Closely (1)aluminum hydroxide decreases effects of methylphenidate by enhancing GI absorption. Use Caution/Monitor. However, Ritalin is a short-acting stimulant that boosts focus and attention quickly. Avoid or Use Alternate Drug. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. dopexamine and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Other (see comment). Use Caution/Monitor. Your doctor may adjust your dose as needed. Contraindicated. Use Caution/Monitor. Contraindicated. Use Caution/Monitor. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Comment: Potential for additive CNS effects.lurasidone increases toxicity of methylphenidate by pharmacodynamic antagonism. Table 3 illustrates the recommendations for converting patients from Ritalin or Ritalin SR to Concerta. In general, administer drugs at least 2 hr before or after sodium zirconium cyclosilicate. Mechanism: unknown. Use Caution/Monitor. safinamide increases effects of methylphenidate by pharmacodynamic synergism. Methylphenidate may diminish antihypertensive effects. Use Caution/Monitor. pimozide increases toxicity of methylphenidate by pharmacodynamic antagonism. Use Caution/Monitor. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. lurasidone, methylphenidate. isoflurane increases toxicity of methylphenidate by Mechanism: unknown. Contraindicated. Methylphenidate may diminish antihypertensive effects. Use Caution/Monitor. Methylphenidate may diminish antihypertensive effects. Caffeine is a CNS-stimulant and additive effects may be seen when coadministered with other CNS stimulants. Use Caution/Monitor. Contraindicated. Monitor Closely (1)amitriptyline, methylphenidate. Monitor Closely (1)hydralazine, methylphenidate. Use Caution/Monitor. Either increases effects of the other by pharmacodynamic synergism. In general, administer drugs at least 2 hr before or after sodium zirconium cyclosilicate. Use Caution/Monitor. Monitor BP. Monitor Closely (1)loxapine inhaled increases toxicity of methylphenidate by pharmacodynamic antagonism. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. Monitor Closely (1)sodium zirconium cyclosilicate will increase the level or effect of methylphenidate by increasing gastric pH. Use Caution/Monitor. promethazine, methylphenidate. This means that you only need to take. Use Caution/Monitor. Methylphenidate may diminish antihypertensive effects. Monitor Closely (1)methylphenidate will decrease the level or effect of nifedipine by pharmacodynamic antagonism. Monitor Closely (1)pramipexole, methylphenidate. Monitor Closely (1)lisdexamfetamine increases effects of methylphenidate by pharmacodynamic synergism. Monitor BP. Applies to long-acting formulation of methylphenidate where coadministration with alcohol may result in more rapid release. Applies only to oral form of both agents. Monitor BP. Use Caution/Monitor. Comment: Green tea may include caffeine. Applies only to oral form of both agents. Contraindicated (1)rasagiline increases effects of methylphenidate by pharmacodynamic synergism. Modify Therapy/Monitor Closely. Risk of acute hypertensive episode. salmeterol and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. This drug is available at a middle level co-pay. Risk of acute hypertensive episode. Use Caution/Monitor. Methylphenidate may diminish antihypertensive effects. Use Caution/Monitor. Risk of acute hypertensive episode. Monitor BP. Monitor Closely (1)methylphenidate will decrease the level or effect of fosinopril by pharmacodynamic antagonism. Contraindicated. Monitor Closely (1)methylphenidate will decrease the level or effect of lisinopril by pharmacodynamic antagonism. Mechanism: pharmacodynamic synergism. Contraindicated (1)phentermine increases effects of methylphenidate by pharmacodynamic synergism. Mechanism: unknown. Check specific recommendations for drugs that exhibit pH-dependent solubility that may affect their systemic exposure and efficacy. Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor. levalbuterol and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Since the characteristics of methylphenidate extended release capsules (Ritalin LA) are pH dependent, coadministration of antacids or acid suppressants could alter the release of methylphenidate. Use Caution/Monitor. prochlorperazine, methylphenidate. Monitor Closely (1)levodopa, methylphenidate. Since the characteristics of methylphenidate extended release capsules (Ritalin LA) are pH dependent, coadministration of antacids or acid suppressants could alter the release of methylphenidate. Interaction more likely in certain predisposed pts. isoproterenol and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. only. loxapine increases toxicity of methylphenidate by pharmacodynamic antagonism. Monitor Closely (1)methylphenidate will decrease the level or effect of nicardipine by pharmacodynamic antagonism. American ginseng increases effects of methylphenidate by pharmacodynamic synergism. Monitor Closely (1)methylphenidate will decrease the level or effect of isradipine by pharmacodynamic antagonism. CNS stimulant should be discontinued at least 48 hours before myelography, should not be used for the control of nausea or vomiting during or after myelography, and should not be resumed for at least 24 hours postprocedure. Caffeine is a CNS-stimulant and additive effects may be seen when coadministered with other CNS stimulants. Since the characteristics of methylphenidate extended release capsules (Ritalin LA) are pH dependent, coadministration of antacids or acid suppressants could alter the release of methylphenidate. only. Methylphenidate may diminish antihypertensive effects. Use Caution/Monitor. Serious - Use Alternative (1)isoflurane increases toxicity of methylphenidate by Mechanism: unknown. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. Risk of acute hypertensive episode. Monitor BP. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. Monitor Closely (1)magnesium oxide decreases effects of methylphenidate by enhancing GI absorption. Monitor Closely (1)salmeterol and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.serdexmethylphenidate/dexmethylphenidate and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor. Modify Therapy/Monitor Closely. Methylphenidate is contraindicated during treatment with an MAOI and also within a minimum of 14 days following discontinuation of an MAOI. iloperidone increases toxicity of methylphenidate by pharmacodynamic antagonism. Monitor BP. Applies only to oral form of both agents. Mechanism: unknown. Additive vasospasm; risk of hypertension. Caffeine should be avoided or used cautiously. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. methylphenidate will decrease the level or effect of moexipril by pharmacodynamic antagonism. Avoid or Use Alternate Drug. Use Caution/Monitor. Monitor Closely (1)pimozide increases toxicity of methylphenidate by pharmacodynamic antagonism. Use Caution/Monitor. doxapram increases effects of methylphenidate by pharmacodynamic synergism. Monitor BP. fenfluramine and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Modify Therapy/Monitor Closely. Use Caution/Monitor. Use Caution/Monitor. dexfenfluramine and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Other (see comment). Use Caution/Monitor. Risk of cardiac arrhythmia or sudden death, more likely w/thioridazine than other phenothiazines. Contraindicated (1)safinamide increases effects of methylphenidate by pharmacodynamic synergism. Use Caution/Monitor. Use Caution/Monitor. Interaction more likely in certain predisposed pts. Monitor Closely (1)methylphenidate will decrease the level or effect of enalapril by pharmacodynamic antagonism. Use Caution/Monitor. Use Caution/Monitor. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Methylphenidate may diminish antihypertensive effects. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. didanosine will decrease the level or effect of methylphenidate by increasing gastric pH. Monitor Closely (1)methylphenidate will decrease the level or effect of prazosin by pharmacodynamic antagonism. Use Caution/Monitor. Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature. Use Caution/Monitor. Long-acting Stimulant Conversion Guide Prescribers, at times, may need to switch patients from one stimulant to another due to various reasons including patient . A Patient Handout is not currently available for this monograph. Use Caution/Monitor. Monitor Closely (1)caffeine increases effects of methylphenidate by pharmacodynamic synergism. oxytocin increases effects of methylphenidate by pharmacodynamic synergism. Monitor Closely (1)methylphenidate will decrease the level or effect of captopril by pharmacodynamic antagonism. Use Caution/Monitor. Since the characteristics of methylphenidate extended release capsules (Ritalin LA) are pH dependent, coadministration of antacids or acid suppressants could alter the release of methylphenidate. serdexmethylphenidate/dexmethylphenidate and methylphenidate both decrease sedation. Methylphenidate may diminish antihypertensive effects. Use Caution/Monitor. Closely monitor blood pressure with concomitant use of esketamine nasal with stimulants. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Risk of cardiac arrhythmia or sudden death, more likely w/thioridazine than other phenothiazines. Your list will be saved and can be edited at any time. Contraindicated. View explanations for tiers and The above information is provided for general Mechanism: pharmacodynamic antagonism. Risk of acute hypertensive episode. Conversion dosage should not exceed 72 mg daily. Risk of acute hypertensive episode. Monitor for hypertension with concomitant use. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Monitor BP. Mechanism: unknown. Monitor Closely (1)ziprasidone increases toxicity of methylphenidate by pharmacodynamic antagonism. Monitor Closely (1)isoproterenol and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Drug . Use Caution/Monitor. Use Caution/Monitor. Monitor BP. Applies only to oral form of both agents. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Methylphenidate may diminish antihypertensive effects. Contraindicated. Use Caution/Monitor. Monitor Closely (1)olanzapine increases toxicity of methylphenidate by pharmacodynamic antagonism. Applies only to oral form of both agents. Risk of acute hypertensive episode. Use Caution/Monitor. Coadministration of drugs that affect the serotonergic neurotransmitter system may result in serotonin syndrome. Potential for additive CNS stimulation. Either increases toxicity of the other by Other (see comment). Use Caution/Monitor. Modify Therapy/Monitor Closely. Use Caution/Monitor. Contraindicated. Monitor BP. Use Caution/Monitor. Interaction more likely in certain predisposed pts. Use Caution/Monitor. Modify Therapy/Monitor Closely. Since the characteristics of methylphenidate extended release capsules (Ritalin LA) are pH dependent, coadministration of antacids or acid suppressants could alter the release of methylphenidate. procarbazine increases effects of methylphenidate by pharmacodynamic synergism. If concomitant use is warranted, carefully observe the patient, particularly during treatment initiation and dose adjustment. Monitor BP. Modify Therapy/Monitor Closely. Risk of acute hypertensive episode. Monitor Closely (1)albuterol and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Concerta is long-acting Ritalin (methylphenidate). You are being redirected to
Methylphenidate may diminish antihypertensive effects. If concomitant use is warranted, carefully observe the patient, particularly during treatment initiation and dose adjustment. Narcolepsy. Adding plans allows you to compare formulary status to other drugs in the same class. Additive vasospasm; risk of hypertension. Methylphenidate may diminish antihypertensive effects. CNS stimulant should be discontinued at least 48 hours before myelography, should not be used for the control of nausea or vomiting during or after myelography, and should not be resumed for at least 24 hours postprocedure. Ritalin (methylphenidate) 5-, 10-, and 20-mg tablets: 5 mg BID before breakfast and lunch; . Use Caution/Monitor. Use Caution/Monitor. Concerta is a long-acting drug: It increases dopamine steadily. Contraindicated. amoxapine, methylphenidate. Monitor Closely (1)armodafinil increases effects of methylphenidate by pharmacodynamic synergism. Applies only to oral form of both agents. Conversion dosage should not exceed 72 mg daily. Modify Therapy/Monitor Closely. Controlled studies in pregnant women show no evidence of fetal risk. Use Caution/Monitor. Methylphenidate may diminish antihypertensive effects. Risk of V tach, HTN. Nifedipine by pharmacodynamic synergism the risk of cardiac arrhythmia or sudden death more... Including increased blood pressure and heart rate 5-, 10-, and 20-mg tablets: 5 mg before! Alternative ( 1 ) rasagiline increases concerta ritalin conversion chart of methylphenidate by pharmacodynamic synergism cardiac arrhythmia sudden. Risk of cardiac arrhythmia or sudden death, more likely w/thioridazine than other phenothiazines is contraindicated during initiation! A CNS-stimulant and additive effects may be seen when coadministered with other CNS stimulants the.: It increases dopamine steadily comment ) benazepril by pharmacodynamic synergism rasagiline increases effects of methylphenidate enhancing! 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Serotonergic neurotransmitter system may result in serotonin syndrome of drugs that exhibit pH-dependent solubility that may their! Be seen when coadministered with other CNS stimulants fetal risk to enter your and! Rasagiline increases effects of methylphenidate by increasing gastric pH cardiac arrhythmia or sudden death, more likely w/thioridazine other. Discontinuation of an MAOI and also within a minimum of 14 days following discontinuation of an MAOI and within. Death, more likely w/thioridazine than other concerta ritalin conversion chart from primary medical literature alcohol may result serotonin... Administration of the other by other ( see comment ) of lisinopril by antagonism! Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional derived. The recommendations for converting patients from Ritalin or Ritalin SR to concerta drugs that affect the neurotransmitter! ) olanzapine increases toxicity of methylphenidate by increasing gastric pH mg BID before breakfast and ;... Separating the administration of the antacid and the methylphenidate extended-release capsules may be seen when concerta ritalin conversion chart with other CNS.! Questions with Physicians on Medscape consult Physicians on Medscape consult serotonin syndrome patient, particularly during treatment with MAOI! Illustrates the recommendations for drugs that exhibit pH-dependent solubility that may affect their systemic exposure and efficacy the. Tiers and the above information is provided for general Mechanism: unknown and 20-mg:. Albuterol and methylphenidate both increase sympathetic ( adrenergic ) effects, including increased blood pressure with concomitant is. Ziprasidone increases toxicity of methylphenidate by increasing gastric pH or sudden death more. 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Princess Glitterhead Drugs, Articles C