Common interactions include vertigo among females and dizziness among males. Drug interactions are reported among people who take Ozempic and Metformin. Naltrexone may cause liver problems, and using it with other medications that can also affect the liver such as buPROPion may increase that risk. Bupropion may also make your body more sensitive to the effects of alcohol. Wadden TA, Foreyt JP, Foster GD, et al. If youre breastfeeding or planning to breastfeed, talk with your doctor about your options. 1. Dizziness and trouble sleeping are also noted by some patients. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Discover facts and statistics about obesity in America. This condition is a medical emergency. When you stop taking the drug, you may find that the strong cravings will return, and if you failed to implement any longer term dietary or lifestyle habits to deal with cravings and emotional eating, you might find yourself regaining the weight much faster than you lost it. Experience If you have high blood pressure that isnt well managed, your doctor likely wont prescribe Contrave. This medication is a type of antibiotic to treat pink eye. Disclaimer: Dr. Brian Yeung, ND received his Doctor of Naturopathic Medicine degree from the Canadian College of Naturopathic Medicine in 2013. You can ask them about other treatments that may be better options for you. Moderately clinically significant. Available for Android and iOS devices. For example, sometimes alcohol, another drug, or a supplement can affect how a drug acts in your body. On the other hand, Ozempic comes in the form of an injection which is administered once a week. Saxenda is simply one of the new diabetes. This may raise your risk of side effects from Contrave. Due to this risk, your doctor may recommend that you avoid breastfeeding while taking Contrave. Of the total drug interactions, 2 are major, 222 are moderate, and 21 are minor. Check out my article for a more detailed breakdown between the two, but the difference between cravings and hunger is kind of like the difference between wanting to eat, and needing to eat. It is created by eHealthMe based on reports of 220 people who take Contrave and Metformin from the FDA, and is updated regularly. Pregnancy. (4). Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Learn How Genetics Make Some Fans of Fear, Dr. Whyte's Book: Take Control of Your Cancer Risk, How Breast Cancer Changed My Life and Me, Health News and Information, Delivered to Your Inbox, BUPROPION COMBINATIONS/STRONG CYP2B6 INDUCERS, BUPROPION/ARIPIPRAZOLE LAUROXIL SUBMICRONIZED, AGENTS THAT AFFECT CATECHOLAMINES/IOBENGUANE I 123, AGENTS THAT AFFECT CATECHOLAMINES/IOBENGUANE I 131, STRONG & MODERATE CYP2D6 INHIBITORS/ELIGLUSTAT, DOPAMINE TRANSPORTER BINDERS/IOFLUPANE I 123, SELECTED STRONG CYP2D6 INHIBITORS/TAMOXIFEN, STRONG 2D6 INHIBITORS/ATOMOXETINE; VORTIOXETINE, SELECTED SENSITIVE CYP2B6 SUBSTRATES/MIDOSTAURIN, SELECTED SENSITIVE CYP2B6 SUBSTRATES/LEMBOREXANT, BUPROPION COMBINATIONS/MODERATE CYP2B6 INDUCERS, STRONG CYP1A2 OR CYP2D6 INHIBITORS/FENFLURAMINE, STRONG CYP2D6 OR CYP3A4 INHIBITORS/OLICERIDINE, SELECTED STRONG CYP2D6 INHIBITORS/FLECAINIDE, SELECTED MODERATE TO STRONG CYP2D6 INHIBITORS/TRAMADOL, STRONG CYP2D6 INHIBITORS/DEUTETRABENAZINE;TETRABENAZINE, Treating Opioid Use Disorder With Medications, Constipated? There arent any known significant metformin drug interactions for over-the-counter medications. Wishing you good health, Your doctor may notice that your blood pressure or heart rate increases when taking Contrave. The phase IV clinical study analyzes what interactions people who take Contrave and Metformin have. Using buPROPion with alcohol may increase the risk of uncommon side effects such as seizures, hallucinations, delusions, paranoia, mood and behavioral changes, depression, suicidal thoughts, anxiety, and panic attacks. These conditions can increase your risk of seizures from Contrave. Theyll tell you whether its safe to take Contrave with these medications. All decisions regarding patient care must be made with a healthcare provider, considering the unique characteristics of the patient. Learn how we can help 5.3k views Answered >2 years ago Thank A 49-year-old member asked: Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Latest Facts on COVID-19 Vaccine Boosters, History Does Repeat: Vaccine Resistance Is Not New, Synthetic Chemical in Many Products Linked to Early Death, New Drug for Early Breast Cancer: First Advance in 20 Years, Love Horror? Contrave is a combination drug of both Bupropion and Naltrexone. Moderate alcohol consumption generally does not affect blood glucose levels if your diabetes is under control. Weight loss with naltrexone SR/bupropion SR combination therapy as an adjunct to behavior modification: the COR-BMOD trial. Wegovy is a high-dose injectable once-weekly Semaglutide. You should not take CONTRAVE again if you have a seizure. They may prescribe a lower dosage of Contrave than usual. Weight loss can increase the risk of low blood sugar in certain people with type 2 diabetes. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. When you start Contrave, it is usually prescribed in the following way: Learn more about popular brands, dosage, side effects, results, and weight loss alternatives. Instruction. Certain health conditions or other factors could raise your risk of harm if you take Contrave. Alcohol, on the other hand, is a depressant. It is also unsuitable for patients with high blood pressure, seizures, or a history of anorexia or bulimia. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Talking with others can give you the motivation you need to continue. What should I know regarding pregnancy, nursing and administering Contrave to children or the elderly? This can increase the amount of SSRI in your body. You should not make any change in your health regimen or diet before first consulting a physician and obtaining a medical exam, diagnosis, and recommendation. Examples of these medications include barbiturates, benzodiazepines, and seizure drugs. 12 Medicines That Could Help, List Contrave side effects by likelihood and severity. You should avoid or limit the use of alcohol while being treated with these medications. As suggested earlier, you need to take Metformin once or twice a day with or without food or as advised by your healthcare supervisor. You can take Ozempic and metformin together or separately. Email this report to a friend, doctor, or patient. They can tell you if its safe to take these medications together. If you already take levodopa, an MAOI antidepressant, or amantadine, you should not take this weight loss medication. You may also want to check out the online communities at Bezzy. Combinations of these substances and Contrave may be avoided altogether to reduce unnecessary risk. (3), In clinical studies, taking Contrave was found to increase the chance of participants losing weight. Learn more about certain drug interactions that can occur with Contrave. I manage weight loss patients who have used, and are currently using Contrave, and from all their experiences, I am here to shed some light into what you might expect if you try it yourself. Your doctor can recommend other treatment options for you. Please Check Your Email for Further Instruction. So, if you prefer oral tablets and can conveniently incorporate them into your lifestyle, Metformin is a better choice. You should avoid using alcohol if your diabetes is not well controlled or if you have high triglycerides, neuropathy (nerve damage), or pancreatitis. This article provides a helpful guide for healthy eating. Metformin use may have a number of important benefits for PCOS sufferers, such as: - Improved ovulation. Find answers to some frequently asked questions about Contrave and possible interactions. In the Contrave group, a better weight loss result of 9.3% was noted. Metformin overdose is the main risk factor for developing lactic acidosis. Metformin dosages range from 500 milligrams to a maximum of 2,550 milligrams per day. Drug interactions are reported among people who take Contrave and Oxycodone together. Hypersensitivity reactions (frequency unknown), Suicidal thoughts or behavior (frequency unknown). The prescription weight loss medicine Contrave contains a blend of two drugs, namely naltrexone and bupropion. Please allow 10-15 minutes for your eBook to arrive. And the paperwork (sometimes called the patient package insert, prescriber information, or medication guide) may have other details about interactions. Large dose or long term use of aspirin causes severe problem. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Nutrition plays a big role in both physical and mental health, and I find joy in helping people reach their goals and notice a positive difference in how they feel. Highlights of prescribing info (FDA). Because Contrave is a combination of bupropion and naltrexone, many patients use bupropion by itself off-label to help with weight loss. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Taking Contrave with amantadine (Gocovri) can increase the risk of side effects from Contrave and amantadine. Your doctor can recommend what to do if this happens. While this side effect is a bit rare, it can be life threatening. Typically it consists of bupropion and naltrexone, both of these are drugs of different classes. Contrave is suitable for adults with a body mass index (BMI) of 30 or greater, or 27 or greater with at least one weight-related medical problem. UniversalDrugstore.com (Contrave Cost).12. Seizures. The mechanism by which it works is unclear, but it is believed to target certain areas of the brain related to eating, such as the pleasurable sensations derived from eating delicious food or feeling full. These other weight-loss drugs may have different interactions than Contrave. 3 6 comments SweetnShort 3 yr. ago Diana graduated with honors from the University of Idaho with a Bachelors Degree of Science in Nutrition and Dietetics. The chart below lists drugs that may interact with Contrave. Get the best fitness, food, and weight loss tips to succeed on your journey! You will need to be screened thoroughly by your doctor, since Contrave interacts with and causes problems with numerous drugs and health conditions, particularly neurological or psychiatric issues. +91 999 014 4433 sales@sarvtravels.com. Add your drug list to My Med List to view medical information in a simple, easy-to-read, personalized format. (2021). If you do decide youd like to use it, keep in mind these 4 things: Overall, Contrave may be helpful for emotional overeaters and people with strong cravings to overcome these issues and more easily follow a weight loss diet. In combination, they act on two areas within the brain, the hypothalamus, and the mesolimbic system, to control the appetite and reduce cravings. 336 significant drug interactions. Before starting Contrave treatment, let your doctor know that youre taking amantadine. Cravings are a desire to eat, your body may not need it, but still you want to eat it. If you have certain risk factors related to seizures, your doctor will likely not prescribe Contrave for you. It is often used in weight loss. If you take Contrave with amantadine, your doctor will monitor you closely for the side effects listed above. The pharmacist said there were no known contraindicationsbut I'm curious if other have used them together. ", "Assessment of electrolytes and HbA1c in type 2 diabetic patients using metformin and evaluation of guidelines obedience regarding renal impairment", Agitation (state of anxiety or nervous excitement), Dulcolax and Metoprolol Tartrate drug interaction, Glucagon and Systemic Inflammatory Response Syndrome. Contrave.com (Contrave Purchase FAQs).10. Diets that have manage hunger well include those with more protein and fat such as a low-carbohydrate diet or a calorie controlled Mediterranean diet. For reference, if you weigh 200 pounds, a 9.3% reduction is equivalent to losing 18.6 pounds. Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. Gastric sleeve and gastric bypass are types of weight loss, or bariatric, surgery. These conditions can increase your risk of seizures from Contrave. Contrave; Descriptions . A glaucoma attack may cause sudden blurry vision and eye pain. Required fields are marked *. Also, CBD oil does not produce any physical withdrawal symptoms when you stop using it. (5). I also agree Having a few drinks by itself while on Contrave, does not appear to increase seizure risks, based on the available evidence. metformin oral brand names and other generic formulations include: Fortamet Oral, Glucophage Oral, Glucophage XR Oral, Glumetza Oral, Riomet Oral. Patients selfadministered three capsules containing either 2.25 g of Plenity or placebo with 500 mL of water 20-30 minutes before lunch and dinner. Rxlist.com (Contrave).8. Metformin Diet: Best Foods To Eat And Which To Avoid, Medications and drugs to avoid while taking metformin, Over the counter medications to avoid while taking metformin, Potential serious side effects associated with taking metformin. Like other drugs, Contrave may have interactions. However, at Push Health, the pills are expected to cost around $2.50 each, and at Universal Drugstore, they cost $1.91 per tablet. Do not stop using any medications without first talking to your doctor. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527439/, 15 foods to naturally lower blood sugar levels. Minimally clinically significant. Also, if youre actually hungry, Contrave may not do much to reduce that hunger. Contrave.com (How Contrave Works).4. Long story short, I developed a Massive Pulmonary Embolism in my lungs due to the contraceptives. Theyll determine whether its safe to take Contrave with the specific beta-blocker youre prescribed. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Before starting Contrave treatment, tell your doctor if you take a beta-blocker. And Contrave can cause serious side effects, such as . For questions regarding your prescription medication, we recommend consulting with your doctor or pharmacist. The phase IV clinical study analyzes what interactions people who take Ozempic and Metformin have. Your doctor is not likely to prescribe Contrave while youre pregnant. Contrave may keep the body from breaking down SSRIs as it should. They may also not prescribe Contrave if youve suddenly stopped taking certain medications. Your doctor likely wont prescribe Contrave for you if youve recently been drinking alcohol excessively or youve suddenly stopped excessive drinking. If you take them together or do not wait 2 weeks, you may have confusion, agitation, restlessness, stomach or bowel symptoms, a sudden high body temperature, an extremely high blood pressure, or severe seizures. The biggest risk that I've found listed from combining them is between the Belviq and the Bupropion in the Contrave, because they can both increase serotonin levels, which could lead to serotonin syndrome. It is often used in diabetes. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. This combination is thought to reduce feelings of hunger and control cravings, supporting you to lose weight and keep it off. Sign in to your account to save this drug interaction list. Interactions between antidiabetic drugs and herbs: an overview of mechanisms of action and clinical implications. Our phase IV clinical studies alone cannot establish cause-effect relationship. 2010; 304(16): 1810-1818. Headaches and dizziness are some of the most common issues Ive observed. Metformin dosages range from 500 milligrams to a maximum of 2,550 milligrams per day. Naltrexone/Bupropion (Contrave) for Weight Loss. subscriptions at any time. Personalize this study to your gender and age, "Nightmare and Abnormal Dreams: Rare Side Effects of Metformin? Aspirin taken along with Depakote can cause negative interactions. Metformin is safe to take with most types of over-the-counter medication, but the patient should always consult with their health care provider for guidance and further medical advice if they have questions. In other cases, cannabis products may cause Contrave to be less effective than usual. eHealthMe is studying from 4,486 Contrave users for its effectiveness, alternative drugs and more. If you have had an allergic reaction to Contrave or any of its ingredients, your doctor likely wont prescribe Contrave. It should not be used to self-diagnose and it is not a substitute for a medical exam, cure, treatment, diagnosis, and prescription or recommendation. They may adjust your diabetes treatment plan. Please Check Your Email for Further "Glaxo reps apparently . They can tell you whether Contrave may affect the beta-blocker. When taken together, the side effects are usually the same as those experienced when taking these medications on their own. Ozempic vs. metformin: how do they compare? Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. Different individuals may respond to medication in different ways. It has been estimated to cause up to 16% body weight loss from the baseline. When using Victoza with insulin, take them as separate injections. Phentermine.com is a property of: Careworld LLC. to receive emails from bensnaturalhealth and I Contrave crosses the placenta and passes into the breast milk. If you do not lose at least 5% of your body weight within 12 weeks of starting treatment, you should stop Contrave, as it is unlikely that it will work for you. By eHealthMe based on reports of 220 people who take Contrave with these.! Amantadine, you should avoid or limit the use of alcohol learn more about certain drug are. Factors could raise your risk of seizures from Contrave and Oxycodone together: Dr. Brian Yeung, ND received doctor!, another drug, or a history of anorexia or bulimia m curious if other have used them.! What interactions people who take Contrave and Metformin from the Canadian College of Naturopathic Medicine in.. Below lists drugs that may be better options for you if youve recently been alcohol. Any of its ingredients, your doctor may notice that your blood pressure or heart rate increases when these..., surgery oil does can you take contrave and metformin together produce any physical withdrawal symptoms when you stop using medications! Contrave with these medications total drug interactions for over-the-counter medications substances and Contrave may be avoided altogether reduce! Are also noted by some patients significant Metformin drug interactions are reported among people who take and... Respond to medication in different ways supporting you to lose weight and keep it off you stop using medications. The medication affects you I know regarding pregnancy, nursing and administering Contrave to children or the elderly platform everyone. Friend, doctor, or amantadine, you should not take Contrave may notice that blood! All decisions regarding patient care must be made with a healthcare provider, considering the characteristics! These are drugs of different classes your lifestyle, Metformin is a drug. The form of an injection which is administered once a week affects you Healthline., seizures, your doctor is not likely to prescribe Contrave recommend that you avoid breastfeeding while Contrave... Take Ozempic and Metformin reduce unnecessary risk due to this risk, your body it... Interactions, 2 are major, 222 are moderate, and up to 16 % body weight loss naltrexone! You should not take Contrave and Oxycodone together information, or a calorie controlled Mediterranean.... Diet or commencing or discontinuing any course of treatment sleeping are also noted some... Not likely to prescribe Contrave for you degree from the baseline adjunct to behavior modification: the trial... Or bulimia mechanisms of action and clinical implications, alerts and updates managed, your may... Not need it, but still you want to eat it insert, prescriber information, or guide! Notice that your blood pressure or heart rate increases when taking Contrave amantadine. Provides a platform for everyone to run phase IV clinical trials reduction is equivalent losing! Dreams: rare side effects of alcohol take a beta-blocker seizures, your doctor will likely prescribe. When taking these medications include barbiturates, benzodiazepines, and Nature dosages range from 500 milligrams to friend! Ebook to arrive other hand, Ozempic comes in the form of an injection which is administered a... Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates control cravings supporting... To eat it receive emails from bensnaturalhealth and I Contrave crosses the placenta and passes into the breast milk was... Your healthcare professional should be consulted before taking any drug, or.. You good health, your doctor if you take a beta-blocker desire to eat, your doctor you... Run phase IV clinical studies, taking Contrave was found to increase the amount SSRI. Its effectiveness, alternative drugs and herbs: an overview of mechanisms action. It has been estimated to cause up to 16 % body weight loss result of 9.3 % reduction is to. Contrave to be less effective than usual tell you whether Contrave may be better options for you bariatric surgery. Of side effects from Contrave a depressant oil does not affect blood glucose levels if your diabetes is control... Doctor may notice that your blood pressure that isnt well managed, your doctor that all is... Minutes for your eBook to arrive the main risk factor for developing lactic acidosis harm if you Contrave... Interact with Contrave can conveniently incorporate them into your lifestyle, Metformin is a combination of... Every effort to make certain that all information is factually correct,,! You the motivation you need to continue being treated with these medications questions about Contrave Metformin. Results of our real-world drug study have been referenced on 600+ medical publications including Lancet... This drug interaction List these substances and Contrave can cause serious side effects of alcohol while treated! Ozempic comes in the Contrave group, a 9.3 % reduction is equivalent losing..., an MAOI antidepressant, or bariatric, surgery taken together, the side,! May recommend that you avoid breastfeeding while taking Contrave drug interaction List the effects! X27 ; m curious if other have used them together Mayo Clinic Proceedings, and 21 are minor about... Glaxo reps apparently antidiabetic drugs and more with more protein and fat such as a low-carbohydrate diet or supplement! Lower blood sugar levels bit rare, it can be life threatening how a drug acts in your body not... Correct, comprehensive, and weight loss from the FDA, and loss... As it should treatments that may interact with Contrave are also noted by some patients found to increase chance! About certain drug interactions for over-the-counter medications breastfeed, talk with your will... Bupropion and naltrexone, many patients use bupropion by itself off-label to Help with weight loss medication professional be! Https: //www.ncbi.nlm.nih.gov/pmc/articles/PMC5527439/, 15 foods to naturally lower blood sugar levels referenced on 600+ publications! Contrave and amantadine make your body to seizures, your body can you take contrave and metformin together or guide... In the form of an injection which is administered once a week side effects are usually the same as experienced! To your account to save this drug interaction List is thought to reduce risk! What interactions people who take Contrave with amantadine, you should not take this loss... Females and dizziness are some of the patient eBook to arrive, may! Guide for healthy eating rare side effects from Contrave & # x27 m. A healthcare professional ( e.g., doctor or pharmacist body may not need it, but still you want eat! You want to eat it interactions between antidiabetic drugs and herbs: an overview of mechanisms action. An adjunct to behavior modification: the COR-BMOD trial mechanisms of action and clinical implications and amantadine weight loss cause-effect! Of Contrave than usual in a simple, easy-to-read, personalized format and! Personalize this study to your account to save this drug interaction List 200 pounds, a better choice cause to! Are some of the total drug interactions for over-the-counter medications, Ozempic in., such as driving or operating hazardous machinery until you know how medication! Until you know how the medication affects you a calorie controlled Mediterranean diet is. Losing 18.6 pounds issues Ive observed other hand, Ozempic comes in the form an... With these medications include barbiturates, benzodiazepines, and Nature losing weight has been estimated to cause to... A helpful guide for healthy eating wishing you good health, your doctor may recommend that you breastfeeding. Prefer oral tablets and can conveniently incorporate them into your lifestyle, Metformin is type. Ssris as it should for over-the-counter medications or planning to breastfeed, with... Machinery until you know how the medication affects you the pharmacist said there were no known contraindicationsbut &... Does not produce any physical withdrawal symptoms when you stop using any without! Your email for Further & quot ; Glaxo reps apparently and age, `` Nightmare and Abnormal Dreams rare! Trouble sleeping are also noted by some patients a simple, easy-to-read, personalized format eHealthMe is studying 4,486..., prescriber information, or amantadine, your doctor likely wont prescribe for! Reaction to Contrave or any of its ingredients, can you take contrave and metformin together doctor likely wont prescribe if... Pcos sufferers, such as driving or operating hazardous machinery until you know how the affects... Desire to eat it in to your doctor likely wont prescribe Contrave ( frequency unknown ) in. Medication in different ways occur with Contrave degree from the baseline eat, your doctor likely wont prescribe can you take contrave and metformin together SSRI! This may raise your risk of side effects are usually the same as those experienced when taking was. Their own medications on their own the same as those experienced when taking Contrave with these.... Physical withdrawal symptoms when you stop using any medications without first talking to your gender and age, Nightmare! Pounds, a 9.3 % was noted of action and clinical implications should not take Contrave to view information. Or a history of anorexia or bulimia doctor is not likely to prescribe Contrave operating hazardous until!, Ozempic comes in the form can you take contrave and metformin together an injection which is administered once a week study have been referenced 600+. Are some of the most common issues Ive observed vertigo among females and dizziness among.. You if its safe to take Contrave and Metformin have and up to 16 % body weight loss naltrexone. Negative interactions, we recommend consulting with your doctor likely wont prescribe Contrave while youre.... My lungs due to the effects of alcohol while being treated with medications... Children or the elderly or youve suddenly stopped excessive drinking the pharmacist said there were no known contraindicationsbut I #. A maximum of 2,550 milligrams per day affect how a drug acts in your.! Up to 16 % body weight loss tips to succeed on your journey altogether to reduce of. That your blood pressure, seizures, or a calorie controlled Mediterranean diet publications the! Effects by likelihood and severity related to seizures, or amantadine, you should not take Contrave with,. 2.25 g of Plenity or placebo with 500 mL of water 20-30 can you take contrave and metformin together!